Als refers to amyotrophic lateral sclerosis, a chronic, progressive neurological disorder. Amyotrophic lateral sclerosis, also known as acromegaly, is a chronic, progressive degenerative disease involving upper motor neurons, lower motor neurons, and their innervated muscles of the trunk, limbs, and head and face. It is often characterized by symptoms such as muscle weakness, muscle atrophy, muscle fasciculations, medullary palsy, and hyperreflexia. The cause of amyotrophic lateral sclerosis is still unclear, often related to genetic factors, lifestyle, occupational exposure, autoimmune function abnormalities, viral infections and other factors. Its treatment mainly includes general treatment and drug treatment. The general treatment includes nutritional management, respiratory support, psychotherapy and so on. Drug treatment should be given according to the patient’s specific situation, such as riluzole tablets, edaravone injection and other drugs can improve the corresponding symptoms of amyotrophic lateral sclerosis according to the doctor’s instructions. If the patient has the above symptoms, it is recommended to go to a professional hospital, and under the treatment of the doctor to carry out relevant medical examinations, after a clear diagnosis, actively cooperate with the doctor’s treatment.