Crohn’s disease biologics commonly used include infliximab, whose price is usually around $8,000 to $13,000 for a single injection, depending on the geographic region and hospital. Crohn’s disease biologics have anti-TNF-α monoclonal antibodies such as infliximab and adalimumab, which are effective in active CD where conventional treatment is ineffective, and can be used to induce remission and maintenance therapy for CD. Other biologics such as vedolizumab, which blocks lymphocyte migration, and utericizumab, which antagonizes the binding of IL-12/IL-23 to the receptor, have also shown promising results. Infliximab is mainly used for Crohn’s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis; its price is different according to different geographic areas, different hospitals, different levels of local consumption and other factors, generally a shot in 8,000 ~ 13,000 yuan. The details are subject to the consultation of local medical institutions. Adverse reactions include headache, abdominal pain, infections such as upper respiratory tract, sinusitis, pharyngitis; patients with heart failure, allergy, etc. are prohibited. Patients should use this drug under the guidance of a doctor; pay attention to rest during the medication, do not stay up late, observe the efficacy of the treatment, any discomfort, timely consultation.