Sleeping at night with a feeling of foreign body blockage in the throat needs to be treated according to the specific causes, such as chronic pharyngitis, reflux pharyngitis, occupational disease, and after a clear diagnosis, choose the general treatment, medication, surgical treatment and other ways. 1. Chronic pharyngitis: chronic inflammation of the pharyngeal mucosa, submucosa and lymphatic tissues, various discomforts in the pharynx, foreign body sensation, burning sensation, dryness. Drinking less water at night while sleeping, chronic pharyngitis symptoms are obvious. Treatment can choose compound borax solution, furacilin solution gargle, iodine containing tablets, silver yellow containing tablets containing to improve the symptoms, at the same time to pay attention to the diet light. 2. Reflux pharyngolaryngitis: gastric contents reflux into the throat, stimulate the mucous membrane of the throat, causing foreign body sensation in the throat. Treatment of spicy stimulation and sweet and sour food, pay attention to dinner, do not overfill, do not eat before going to bed. Treatment of acid-suppressing drugs and gastrointestinal power drugs, such as omeprazole, moxabepril hydrochloride and other drugs. 3. Occupying disease: hypopharyngeal cancer, laryngeal cancer and other malignant tumors can cause the phenomenon of foreign body blocking feeling in the throat at night, which need to take surgical treatment to remove the diseased tissues through surgery, and cooperate with radiotherapy when necessary. Medications must be applied under the guidance of a doctor. There are many reasons for the feeling of foreign body blockage in the throat at night, after the symptoms appear, it is recommended to go to the hospital in time to improve the examination, and take standardized treatment according to the doctor’s instructions, and do not treat it randomly, so as not to lead to adverse consequences.