Suddenly a large patch of bumps on the body may be due to urticaria, papular urticaria, nodular itchy rash, folliculitis and other factors, need to clarify the cause of the symptomatic treatment, common therapeutic drugs such as loratadine, cetirizine, dinexed cream and so on. 1. Urticaria: related to contact with allergic substances and autoimmune disorders, manifested as a lumpy elevation of varying sizes, bright red or pale white, accompanied by itching. Generally no special treatment, can be in about 24 hours gradually subside, itching is obvious in the doctor’s guidance can be used under the guidance of loratadine, cetirizine and other antihistamines, and actively looking for allergens, to avoid re-exposure. 2. Papular urticaria: It is a skin allergic and inflammatory reaction that occurs after localized skin is stung by insects, manifested as sudden red spots of varying sizes, mostly accompanied by itching. Under the guidance of a doctor, you can use Dinaid cream, flufenamic acid butyl ester ointment topical application, itching intense oral benadryl, ebastine and other antihistamine drugs. 3. Nodular itchy rash: is a huge itch and nodular damage as the main features of inflammatory skin diseases, may be related to mosquito bites, endocrine disorders and other factors, oral loratadine, cetirizine and other antihistamines to stop the itching, topical halomethasone, butyric acid hydrocortisone and other hormonal drugs coated with oral thalidomide, or to the lesions to the injection of hormones for treatment if necessary. Suddenly got a piece of big goosebumps on the body may also be due to other factors, it is recommended that patients seek medical attention in a timely manner, a clear diagnosis, symptomatic treatment, the drug should be used in accordance with the doctor’s instructions.