Percutaneous transvertebral foramen lumbar interbody minimally invasive fusion is the most minimally invasive fusion procedure for the treatment of lumbar discogenic low back pain and lumbar disc herniation. The operation requires only three surgical incisions of about 7 mm in length; no damage to the paravertebral muscles; no damage to the stability of the spine; no harassment in the spinal canal and no adhesion formation in the spinal canal; no lumbar spine surgery failure syndrome occurs; and quick recovery with minimal side injuries. Wang**, female, 54 years old. Complains of intractable lumbar pain for 4 years. MRI of lumbar spine showed degeneration of L5S1 intervertebral disc and inflammatory changes in the adjacent vertebral plate; there was no significant protrusion of L5S1 intervertebral disc and no significant stenosis of the spinal canal. The L5S1 disc and cartilage endplates and other tissues were removed under fluoroscopic X-ray monitoring. The surgical incisions were three 7-mm minimally invasive incisions. A postoperative review CT 1 year later showed a well positioned intervertebral fusion with interbody implant fusion. Postoperative repeat CT 3D reconstruction showed satisfactory interbody fusion of L5S1 vertebrae.