Whether it is useful to take progesterone without menstruation can not be generalized, its treatment has systemic treatment, hormone treatment, surgical treatment, etc., symptomatic treatment will be useful. 1. Systemic treatment: Improve the physical condition of the body, supply enough nutrition, maintain standard weight, and if the amenorrhea is caused by psychological factors, it should receive psychological treatment. 2. Hormone therapy (1) Sex hormone supplementation therapy: the drugs dydrogesterone, medroxyprogesterone acetate and estradiol valerate can be used, mainly to promote and maintain secondary sexual characteristics and menstruation. (2) Ovulation promotion: For those with fertility requirements, the drugs clomiphene, bromocriptine and thyroxine can be used. (3) Surgical treatment: If there are organic diseases such as genital malformations, pituitary tumors, etc., appropriate surgical methods should be chosen according to the actual situation. If menstruation does not come, you should consult a doctor in time and choose a suitable treatment under the guidance of a professional doctor.