Amyloidosis nephropathy is a disease caused by amyloid deposition in the kidneys, the main clinical manifestation is nephrotic syndrome, and the advanced stage can lead to death from renal failure.
Renal amyloidosis kidneys are often enlarged in size in the early stage, hard, pale and swollen in appearance, and granular in surface. In the late stage, when long-term hypertension and/or infection, vascular involvement and stenosis, the volume of the kidney can be seen to decrease, and the clinical manifestations are divided into preclinical stage, proteinuria stage, nephrotic syndrome stage and renal failure stage.
In addition to glomerular involvement, tubular and interstitial involvement can be seen, which manifests as polyuria, or even urolithiasis, with low and fixed urine specific gravity. Renal glycosuria, tubular acidosis, and occasionally typical Fanconi syndrome (Fanconi syndrome) are seen in a few cases.
Patients with amyloid nephropathy should go to the hospital in time and receive standardized treatment under the guidance of professional physicians.