Non-atrophic gastritis with multiple polyps may become cancerous, but the chance of cancer is very low, and it should be actively standardized treatment. Non-atrophic gastritis with multiple polyps belongs to a type of chronic gastritis, due to the repeated stimulation of inflammation caused by the gastric mucosa bulge to form polyps, most of them are inflammatory polyps, and the chance of cancer is very low, but it is also necessary to give standardized treatment. If there is Helicobacter pylori infection, it can be given quadruple therapy treatment, commonly used drugs are amoxicillin, metronidazole, colloidal bismuth pectin, rabeprazole, etc. Through standardized use of medication to cure Helicobacter pylori, some of the multiple polyps may subside. Surgical resection may be considered for polyps larger than 2 centimeters in diameter or progressive enlargement. For non-atrophic gastritis with multiple polyps, it is recommended to consult a doctor as soon as possible and follow the doctor’s instructions.