Sleeping on your back will hold your breath and wake up, may be caused by obstructive sleep apnea syndrome, more considerations may be related to excessive obesity, anatomical narrowing of the upper airway, endocrine factors and other factors. 1. Excessive obesity: excessive obesity in the population of its excess fat is easy to deposit in the upper airway area, resulting in upper airway lumen narrowing and obstruction, or too much obesity in the chest and abdominal fat accumulation, resulting in the collapse of the upper airway, etc., may be triggered by obstructive sleep apnea syndrome, which may appear to sleep on the back will be holding their breath and waking up. 2. Anatomical narrowing of the upper airway: usually due to congenital developmental deformities of the upper airway lumen structure, nasal polyps, vocal polyps, tonsil hypertrophy and other reasons, resulting in narrowing of the upper airway, resulting in airflow obstruction, which triggers Obstructive Sleep Apnea Syndrome, which can cause waking up from sleeping on the back with suffocation of air. 3. Endocrine factors: common in hypothyroidism, diabetes, Cushing’s syndrome and other diseases, may trigger obstructive sleep apnea syndrome, thus showing the phenomenon of sleeping on the back and waking up. Sleeping on your back will hold your breath and wake up, may also be caused by other reasons, you should consult a doctor as soon as possible, a clear diagnosis, and follow the doctor’s instructions for treatment.