Hepatitis B two-to-one 145 positive, what we call the two-to-one half, which is the most commonly done clinical test for hepatitis B infection or not. It is called the two-to-one test, which consists of five items, namely hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B e antigen, hepatitis B e antibody and hepatitis B core antibody. 145 positive means positive surface antigen, positive e antibody and positive core antibody, which is a classic chronic hepatitis B carrier, whose two-to-one test pattern generally indicates a low level of hepatitis B virus replication, but there are However, in a small number of patients, the hepatitis B virus may mutate, and even if the patient is a small triple positive with negative e antigen, there can still be a high level of hepatitis B virus DNA replication, and such a person is often accompanied by significant abnormalities in liver function. Therefore, small triple positive hepatitis B does not mean that treatment is needed or not, it only represents a chronic state of hepatitis B infection. Whether treatment is needed depends on the level of hepatitis B virus DNA replication and whether liver function is normal or abnormal.