Pulsatilla can play an auxiliary role in the treatment of sinusitis, which is caused by inflammation of the nasal cavity and sinuses as a bacterial infection. Clinical manifestations are nasal congestion, runny nose and headache. Examination of the nasal cavity reveals enlarged turbinates, more purulent secretions in the middle nasal passage, etc. Sinus CT shows that the diagnosis can be confirmed. For conservative treatment of sinusitis, oral antibiotics can be taken to kill the bacteria, such as oral clarithromycin, nasal spray trimethoprim, etc. The treatment course is about 10-14 days. Pu Di Lan is a proprietary Chinese medicine, which has the effect of clearing heat and detoxification, and only has an inhibitory effect on bacteria. Taking busulfan alone is less effective in the treatment of sinusitis, and it needs to be combined with the above-mentioned drugs to achieve good results.