Cheek bone pain according to the specific causes of pain, clinical treatment can be taken different methods. First, if it is an acute purulent infection in the oral cavity, caused by the cheek bone pain, such as gum abscess, tooth ulceration, at this time we need to actively control the oral infection, oral metronidazole tablets. Severe symptoms can be ulcerated teeth extraction, oral infection control, local pain symptoms can be gradually relieved. Cancer pain caused by malignant tumor in the oral cavity invading into the cheek bone, at this time, the pain of patients often can not be completely relieved by drugs, it is recommended that the patients improve the head CT or MRI examination, to clarify the location and size of the tumor in the oral cavity, and perform complete tumor removal. After surgery, combined with local radiotherapy and systemic chemotherapy to inhibit the recurrence of tumor cells, can effectively improve the symptoms of cheek bone pain.