Muscle twitching next to the nose may be physiological factors, or facial muscle spasm, Tourette’s syndrome and other diseases. 1. Physiological factors: if the mental stress is relatively large, excessive tension or anxiety, etc., may cause physiological muscle twitching next to the nose, generally through sufficient rest, timely stabilization of emotions can be relieved. 2. Pathological factors (1) Facial muscle spasm: this disease may be caused by mechanical stimulation, facial nerve compression or poor recovery from facial nerve paralysis. The symptoms of twitching on one side of the face may appear, especially in the case of mental overstress, overfatigue, etc., the symptoms are obviously aggravated. (2) Tourette’s syndrome: Tourette’s syndrome also causes involuntary twitching next to the nose, usually accompanied by blinking, grinning, shrugging, and other symptoms, but is usually seen in children. It is recommended that patients seek timely medical attention to clarify the cause and actively cooperate with the doctor’s treatment.