Patients with coronary artery disease are not recommended to stay up late, because staying up late can lead to aggravation of coronary artery disease. Patients who stay up late will stimulate the activation of the renin-angiotensin aldosterone system in the body, which will cause the secretion of excessive angiotensin in the body, leading to an increase in the load on the heart and causing a secondary increase in blood pressure. In addition, staying up too long will stimulate the sympathetic nerve, resulting in sympathetic overexcitation, patients will have chest tightness, shortness of breath, palpitations, arrhythmia, tachycardia and a series of symptoms. When patients with coronary heart disease stay up late for a long time, it will increase the load on the heart and blood vessel cavity, and also lead to conditions such as plant nerve dysfunction. All of the above have a negative impact on patients with coronary heart disease, so patients with coronary heart disease who stay up late for a long time will be greatly detrimental to their health.