When pain occurs in the piriformis muscle, the first thing to do is to clarify the cause of the disease, and then carry out the corresponding treatment. If the pain is caused by trauma, it can be treated conservatively with oral anti-inflammatory and analgesic drug Loxoprofen sodium, intermittent cold compresses can be applied locally within two days of the injury, and local hot compresses can be applied locally after two days of the injury, do not massage, elevate the affected limb to avoid excessive prolapse. If the pain is caused by local purulent infectious diseases, you need to choose sensitive antibiotic anti-infective treatment, local elevation, application of anti-inflammatory and analgesic drugs for symptomatic treatment, if there is pus formation, need to incise and drain. If there is localized space-occupying disease, surgery is needed to release the localized space-occupying. If the radiating pain is caused by nerve root type cervical spondylosis, you can also use inflatable cervical brace to traction the cervical spine, intravenous mannitol injection to dehydrate and reduce the swelling treatment, apply anti-inflammatory and analgesic drugs Loxoprofen sodium, nutritive neurological treatment of methylcobalamin tablets.