The mainstay of acute superficial glans is topical or oral medications. Acute superficial glans is usually caused by bacterial, fungal and other infections, sometimes related to local irritation. Patients can use topical drugs or oral drugs for treatment as follows: 1.Topical drugs: (1) If the glans is caused by bacterial infection, patients can use boric acid water and isacridine solution to wash the glans penis. (2) If the glans is caused by candida infection, patients can use sodium bicarbonate solution to wash the affected area, or use miconazole ointment, clotrimazole ointment, etc. to smear the affected area. (3) If it is trichomonas glans, patients can use potassium permanganate solution to rinse the glans and the inner side of the foreskin. 2. Oral medication: patients can take antibiotics such as gentamicin, erythromycin, metronidazole, or antifungal drugs such as itraconazole as prescribed by the doctor, and some patients may also use hydrocortisone, tacrolimus, vitamins, and other medications for treatment. It is recommended that patients seek timely medical treatment, standardize the use of drugs under the guidance of the doctor, and actively carry out treatment.