Recurrent rectal cancer with large lump at anus after surgery can be treated by surgery, chemotherapy and radiotherapy. 1. Surgical treatment: For patients with recurrent rectal cancer, surgical resection is still the main treatment method. The large anal mass is removed through surgery, and pathological examination is needed to clarify the nature of the mass. 2. Chemotherapy: according to the specific condition of patients, they can choose chemotherapy program and chemotherapy time under the guidance of doctors. At present, chemotherapy drugs for rectal cancer mainly include oxaliplatin, fluorouracil, irinotecan and other drugs. 3. Radiation therapy: if the recurrent rectal cancer has metastasis, it is necessary to combine with radiation therapy on the basis of chemotherapy or after surgery to reduce the local recurrence rate. Immunotherapy and targeted therapy can also be chosen for rectal cancer. Specific treatment plan needs to follow the doctor’s prescription, and it is recommended that patients actively cooperate with the doctor’s treatment in order to improve the prognosis and quality of life.