Barrett’s esophagus is more likely to develop esophageal cancer, and studies have shown that Barrett’s esophagus is an important risk factor for the development of esophageal adenocarcinoma. Barrett’s esophagus refers to the pathological changes that occur in the lower esophagus where squamous cells are replaced by columnar epithelium. Adenocarcinoma originating in the esophagus accounts for about 5% to 10% of esophageal cancers. 86% of esophageal adenocarcinomas originate from Barrett’s esophagus, so-called Barrett’s esophagus carcinoma, and the remaining 14% originate from esophageal mucosal glands and ectopic gastric mucosa. In addition, Barrett’s esophagus is the most important risk factor for the development of esophageal atypical hyperplasia and adenocarcinoma, and the risk of esophageal adenocarcinoma in patients with Barrett’s esophagus is 30-60 times higher than that of normal people. Therefore, Barrett’s esophagus has a high probability of developing esophageal cancer. If you feel sick, it is recommended that you seek medical advice and treatment promptly.