Whether creatinine 128 μmol/L is serious depends on the cause of its elevation. If the cause is physiological or acute kidney injury leading to elevated creatinine, creatinine may return to normal after removing the influencing factors, and it is usually not serious. If the elevated creatinine is caused by chronic kidney disease, with the progress of the disease, it may develop into uremia, which is relatively serious and needs to be treated according to the cause.
Normal serum creatinine ranges from 53 to 106 μmol/L in men and 44 to 97 μmol/L in women. A creatinine of 128 μmol/L is considered mildly elevated. Some elevated creatinine may be caused by the patient’s own high muscle content, or eating more meat and exercising more in general. If it is clear that there is no kidney disease, this kind of situation is usually not serious and does not require special treatment.
Acute kidney injury leading to elevated creatinine, such as sepsis and other causes need to actively control the infection, blood volume insufficiency caused by the need to replenish blood volume, obstructive nephropathy caused by the need to release the obstruction. By removing the causes of acute kidney injury, most of the conditions can be reversed and renal function may return to normal, so it is not considered serious.
Chronic kidney disease causing elevated creatinine, the treatment is mainly to treat the primary disease, lowering blood pressure, lowering urinary protein, and delaying the progression of renal function. Commonly used drugs include captopril and valsartan, and even immunosuppressants such as prednisone and cyclophosphamide will be applied. If the treatment effect is not good, it may progress to uremia, which is relatively serious at this time.
All of the above medications should be used under the guidance of a doctor. If the blood creatinine is found to be elevated, it is recommended to go to the hospital in time for symptomatic treatment.