We know that the main manifestation of dyspepsia is pain or discomfort in the upper abdomen, manifested by bloating, early satiety, feeling full after eating, nausea and other symptoms. According to the epidemiological data, we know that the incidence of dyspepsia is quite common, in foreign countries the general population can reach 7% to 41%, a group of reports in Guangdong reached 18.9%, Tianjin reported that 23.3%. When we look at the situation in hospitals, the general outpatient clinic reaches 11%, while the gastroenterology clinic reaches 53%, which shows that dyspepsia is a very common disease. What causes can cause dyspepsia. We know that there is a large group of diseases that can cause indigestion. For example, gastrointestinal lesions: gastric cancer, ulcer disease, reflux esophagitis, gastritis; and diseases related to gastric dynamics: diabetes, scleroderma, post-surgical gastroparesis; and anorexia nervosa, which I saw this morning. The patient can’t eat because he thinks people say he’s gained a little weight, so in a short time, tens of kilos fall off. Such cases, of course, are also caused by some drug factors. In addition to this, we now find that there are many patients who cannot be detected after many tests, and this category is now called functional dyspepsia. What is the definition of functional dyspepsia according to the Rome III diagnostic criteria. It is defined as having a feeling of discomfort or pain in the upper abdomen for at least 12 weeks in the past year, and the symptoms can be continuous or recurrent. However, an examination does not reveal the cause, or a lesion is found that does not explain its symptoms. Then functional dyspepsia can be classified as dyskinesia, ulcer-like type or non-specific type according to the clinical characteristics. The so-called power disorder type refers to the symptoms of early satiety, bloating, fullness and nausea, which are aggravated after meals. The ulcer-like type is (predominantly) epigastric pain that appears on an empty stomach and decreases after a meal. If the epigastric distress of these patients does not depend on the first type and does not depend on the second type, then we will classify it as non-specific. We must ask how functional dyspepsia is caused. We know from our research that it is related to power disorders and visceral sensory hypersensitivity. Many studies have proved that local stimuli, such as food factors, biological factors or inflammatory factors, as well as neurological abnormalities, central nervous system regulation, psychological factors, autonomic disorders and enteric nervous system dysfunction, may be involved in the development of functional dyspepsia. So we first look at how much gastrointestinal dysfunction in functional dyspepsia, about 50% of the patients will have dysfunction, the main performance (is) what. After eating, the proximal end of the stomach does not open, a meal stays in the stomach for a long time, and then can not be discharged, this is the main problem. There is also the sensory disorder mentioned just now. What is the sensory disorder? It means that people do not feel anything when they are slightly (eaten) into something or slightly stimulated, but these patients are very sensitive. Not necessarily he has a special power problem, he feels hypersensitive, and now it is found that this sensory hypersensitivity is not only in the stomach, the entire gastrointestinal tract have similar conditions. Just now mentioned physical disorders, psychological disorders. We know that nowadays the pace of society is very fast and stressful, so psychosocial and emotional depression plays a very important role in the development. Sometimes we see patients very unhappy, unhappy patients can not eat a lot of things, which led to a disease, this is also seen a lot. The evaluation of functional dyspepsia treatment, in general, the selection of drugs is based on speculation of its possible pathophysiology and pathogenesis. The first-line treatment is mainly prokinetic and acid suppressants, and if the patient has anxiety and depression, antidepressants should be used. And the efficacy of the drug is evaluated for at least one to two weeks. If it is ineffective, it should be re-evaluated and the medication should be changed or combined. Of course, during the follow-up, care must be taken to consider whether our diagnosis is accurate and to consider whether there is organic disease.