Perianal eczema may be related to contact with allergens, genetics and other factors, manifested as erythema, papules, blisters, vesicles and other symptoms, accompanied by itching obvious. Acetic acid white test for warts diagnostic auxiliary means of examination, positive performance for external 5% glacial acetic acid 2-5 minutes after the lesions become white, this is due to the human papillomavirus infected cells and normal cells produce keratin is different, encounter glacial acetic acid can change to white. Perianal eczema is not caused by HPV infection, so it will not turn white when it meets acetic acid. Once the diagnosis of perianal eczema is confirmed, it is recommended to go to the hospital in a timely manner for treatment, and active treatment can effectively improve the symptoms.