Stomach cancer in advanced stage does not necessarily hurt, and even if it hurts, it can often be relieved with timely treatment. Stomach cancer in advanced stage is often accompanied by metastasis to distant organs, which is considered incurable clinically. If the lesion violates nerves, peripheral organs, bone metastasis, etc., pain will appear, which needs timely pain relief treatment to alleviate the pain and improve the quality of life. Those whose lesions have not invaded nerves have better treatment effect, and those with relatively small tumor load often have no obvious pain symptoms, and these patients often have better quality of life. Although it is difficult to cure advanced gastric cancer, in recent years, through more therapeutic means, it is also able to improve the quality of life and prolong the survival period, and the efficacy has been greatly improved compared with the previous treatment.