Cold and flu body aches and pains are mostly seen in influenza, a few can also be seen in the common cold. Usually, influenza is mostly seen in winter and spring seasons, the clinical manifestations of headache, high fever, fatigue, muscle aches and pains, and other systemic symptoms, respiratory symptoms are lighter. The common cold is characterized by upper respiratory symptoms such as cough, runny nose, nasal congestion and sore throat, and systemic symptoms are mild. Muscle aches and pains may also occur if the fever of the common cold is high. The prognosis of simple influenza is generally good. Patients can take antiviral drugs such as oseltamivir granules within 48 hours after the onset of influenza under the guidance of a doctor, which can inhibit the replication of influenza viruses, reduce the pathogenicity of influenza, alleviate the symptoms, and minimize complications. The common cold can be treated without medication if the symptoms are mild, or with symptomatic treatment such as acetaminophen if the symptoms are severe. Therefore, if the patient has a cold and body aches, should consult a doctor in a timely manner, improve the relevant examination, and give targeted treatment. The above drugs should be used under the guidance of a professional doctor, avoid self-medication.