Enlarged nose pores may be related to acne, seborrheic dermatitis and other factors, you can make the pores of the nose smaller through daily care, medication and physical therapy. 1. Daily care: Ensure sufficient sleep, avoid staying up late, and participate in appropriate physical exercise; avoid spicy, stimulating, greasy, and sweet foods, and quit smoking and drinking; pay attention to the cleanliness of the nose area, but do not excessively rub or squeeze. 2. Medication: Under the guidance of specialists, actively carry out the treatment of the original disease, such as acne resulting in enlarged pores can be used Vitamin A acid ointment, clindamycin ointment and other medications; seborrheic dermatitis resulting in enlarged pores can be used tacrolimus cream, ketoconazole lotion and other medications. 3. Physical therapy: after the above treatment effect is not good, or the condition is more serious can consider joint physical therapy, such as fractional laser treatment, fruit acid peeling treatment, intense pulse light therapy. It is recommended that patients who want to reduce the size of their nose pores go to a regular medical institution to clarify the cause of the disease and carry out targeted treatment.