Epilepsy itself does not cause brain atrophy; epilepsy is not a cause of brain atrophy, but it can occur at the same time. Epilepsy is a chronic brain disorder with recurrent seizures, and the cause is related to a variety of factors, generally thought to be related to excessive neuronal discharge in the brain. Symptoms of the disease can be effectively controlled with aggressive treatment. Different types of epilepsy have different symptom characteristics, in addition, epilepsy will cause certain damage to the brain if repeated seizures, need to go to the regular hospital in time for examination and treatment. Brain atrophy is mainly related to aging or brain damage and other factors, mainly manifested in memory, behavioral changes, personality changes and so on. Partial atrophy of the brain may cause epilepsy, and epilepsy caused by atrophy of the brain may manifest in different forms, such as repeating an action, loss of consciousness, convulsions, etc. In addition, a variety of diseases affecting the brain may cause epilepsy. Brain atrophy can also occur in a variety of diseases that affect the brain, such as stroke, traumatic brain injury, multiple sclerosis and Alzheimer’s disease. If symptoms of epilepsy or cerebral atrophy occur, it is recommended to seek medical attention in a timely manner and take active and correct treatment under the guidance of a specialist.