Cirrhotic nodules should be taken seriously. Cirrhosis is a chronic, progressive, diffuse end stage of liver disease caused by the long-term effects of viruses, immunity to alcohol, parasites, carbon tetrachloride and other poisons on the liver, which is based on extensive necrosis of hepatocytes and produces diffuse hyperplasia of hepatic fibrotic tissues, the formation of nodules, pseudo lobules, and ultimately causes damage to the normal structure, function and blood supply of the liver. Nodules in the early stage of cirrhosis can be benign and do not cause damage to liver function, so there is no need to worry too much. However, in the middle and late stages of cirrhosis, the liver is further damaged, causing the liver to shrink in size, and abnormal tissues such as fibrous septum and pseudo lobe appear, which is manifested as cirrhosis with nodules in ultrasound examination, and at this time, it can be accompanied by symptoms such as ascites, vomiting blood, and blood in stools, which is a serious situation. Cirrhosis with nodules is recommended to consult a doctor in time for a clear diagnosis and targeted treatment under the doctor’s guidance.