Generally sponge kidney is not serious, but it is more serious if it is not treated in time after repeated urinary tract infections, urinary stones and other symptoms. Sponge kidney, also known as medullary sponge kidney, is a common clinical condition of congenital abnormalities of renal development. Since, in most cases, this disease has no clinical symptoms and does not affect renal function, so generally medullary sponge kidney is not serious, the prognosis is good, if there are no symptoms or complications, there is no need for treatment, and annual review of urine calcium and urine bacterial culture can be. However, if patients have recurrent urinary tract infections, urinary stones, causing hematuria, renal colic and other symptoms, and do not go through standardized treatment in time, to a certain extent, it will cause damage to the kidneys, which is relatively more serious at this time. To summarize, patients with medullary sponge kidney need to strengthen their daily life management, go to the hospital for review on time, closely monitor the changes in their condition, and actively cooperate with the doctor’s treatment if necessary, so as to avoid delaying their condition.