Most of the Mycoplasma Liberans infections are transmitted due to sexual intercourse, but they can also carry mycoplasma themselves and must be treated if they have symptoms. The patient has to take doxycycline hydrochloride tablets which can be effective, but many patients who also have mycoplasma infection are resistant to the drugs used to treat this pathogen, such as doxycycline, erythromycin, roxithromycin and tetracycline, so they must be treated by bacterial culture plus drug sensitivity, which will soon be available according to the results of the drug sensitivity. The course of treatment for Mycoplasma Liberans is 12-14 days, so if treatment is needed, it must be a full course of treatment, with both spouses treated at the same time.