Retroperitoneal paragangliomas can be malignant or benign. Retroperitoneal paraganglioma is a tumor of paraganglia, mainly located in abdominal aorta, common iliac artery or the beginning of mesenteric artery, etc. Most of the tumors are benign, and only about 20% of the tumors are malignant. It should be noted that, no matter whether it is benign or malignant retroperitoneal paraganglioma, once the diagnosis is confirmed, the patient needs to cooperate with the doctor actively to carry out the treatment. Clinically, surgery can be used to remove the tumor, and family members need to accompany the patient frequently, give the patient enough security, let the patient actively cooperate with the doctor for treatment, and pay attention to the regularity of diet, with reasonable combination of meat and vegetables, eat more fresh vegetables and fruits, and regulate the metabolic process of the patient. After the operation, the patient should go to the hospital for regular checkups, and if there is any abnormality, the patient should consult the doctor immediately.