Children with a high fever of 40 degrees and cold hands and feet, do not worry excessively, usually not a critical phenomenon. If the mental state is relatively good, good diet, normal urine and stool, you can take oral antipyretic and analgesic drugs such as ibuprofen and acetaminophen, which can play a fast role in reducing fever. A child with a high fever of 40 degrees and cold hands and feet usually has cold hands and feet because of poor blood circulation in the limbs during the period of rising body temperature. This is when parents give medication to reduce fever while using physical cooling methods to assist the body temperature to drop.