Equine tetanus immunoglobulin is effective in preventing serious complications caused by tetanus infection. A negative skin test is required before an intramuscular injection of tetanus immunoglobulin can be given; if the skin test is positive, a skin-free tetanus immunoglobulin injection is also required. If a person’s body is stabbed by a nail or trauma and the wound is small on the surface and deep inside, this condition can achieve anaerobic conditions. If there is a tetanus bacillus on the external object, it may lead to the multiplication of tetanus bacillus inside the wound and cause the human body to be infected with tetanus, which can be prevented by using horse tetanus immunoglobulin at this time.