Nausea and vomiting after drinking coffee may be caused by indigestion, reflux esophagitis, gastritis and other diseases. 1. Indigestion: Nausea and vomiting after drinking coffee may be caused by indigestion. The etiology of dyspepsia is related to gastrointestinal dyskinesia, visceral sensory hypersensitivity, Helicobacter pylori infection, irregular meal times, and excessive coffee intake. Patients may experience pain in the upper and middle abdomen, nausea and vomiting. 2. Reflux esophagitis: Reflux esophagitis may be caused by factors such as decreased esophageal clearance, delayed gastric emptying, obesity, and esophageal sensory abnormalities. Patients may have symptoms such as painful epigastric pain, belching (hiccups), etc. Some patients may experience nausea and vomiting after drinking coffee. 3. Gastritis: Gastritis may be caused by alcohol, drugs, trauma, Helicobacter pylori infection, autoimmune function abnormality, gastric mucosal degenerative disease and other factors. Patients will experience symptoms such as discomfort in the upper and middle abdomen, abdominal distension, and nausea and vomiting when they drink coffee. There are many reasons that lead to nausea and vomiting after drinking coffee, and it is recommended that patients identify the causes of the disease in a timely manner.