The viral load is usually higher in patients with Major Triple Yang Hepatitis B because this is not a Minor Triple Yang. The higher hepatitis B E antigen in a major triple-positive patient indicates that the hepatitis B virus is more actively replicating in the body and a high viral load is a more natural phenomenon. High aminotransferases, most likely elevated glutamic alanine and glutamic oxalacetic aminotransferases, indicate that there is destruction of liver cells, and the extent of liver cell destruction can be generally judged by the degree of aminotransferase elevation. If the aminotransferase elevation is more obvious, it means that the destruction is more serious, so we can carry out liver preservation and enzyme lowering treatment according to the current situation. If the degree of transaminase elevation is relatively mild, you can try oral liver-protective drugs; if it is more severe, it is better to apply relevant drugs intravenously; if the transaminase is particularly high or repeatedly elevated and cannot be reduced to normal, it is recommended to take oral nucleoside analogues at the same time to control the replication of the virus.