When a patient has an imbalance of air pressure in the ear, the most important thing is that there is a negative pressure in the middle ear cavity, which mainly occurs in patients with secretory otitis media. In order to solve the imbalance of ear pressure, we need to treat the underlying causes, such as medication, tympanic membrane puncture and fluid extraction treatment, etc., as follows: 1. Medication: Patients often suffer from cold or respiratory tract infections that cause dysfunction of the eustachian tube, which further leads to negative pressure in the middle ear. If the patient’s symptoms do not improve after long-term treatment, or even further produce If the patient’s symptoms do not improve after long-term treatment, or even if further fluid accumulation in the middle ear occurs, tympanic membrane puncture and fluid extraction treatment is required.