Always feel no spirit, no strength, the appearance of the above phenomenon need to be alert to the following diseases: 1, depression: depression has three core symptoms, such as depressed mood, unhappy, reduced interest, the third is reduced energy, fatigue, if the above three groups of symptoms last more than two weeks, also accompanied by sleep disorders, various types of pain, etc., need to be alert to depression. 2, other: also be alert to the patients have Physical diseases, such as long-term anemia, and heart disease, which will lead to ischemia and hypoxia of the brain and systemic tissues and organs, resulting in lack of energy and spirit, but also pay attention to whether there is food poisoning, nutritional deficiencies and so on. In addition, chronic diseases, such as early tumors, leukemia, etc., can lead to the above phenomena, and need to go to the hospital to do relevant tests to clarify the diagnosis.