Megacolon in children is also known as megacolon. The diagnosis of megacolon can be confirmed by the patient’s symptoms combined with physical examination and X-ray examination. It is recommended that the patient go to a local specialized hospital as soon as possible to prevent misdiagnosis or missed diagnosis. Children with megacolon are often characterized by delayed evacuation of fetal stool, abdominal distension, diarrhea, constipation, etc. Physical examination reveals signs such as varicose veins on the abdominal wall, intestinal shape and peristaltic wave, etc. Anal fingerprinting can be used to find out the degree of tension of internal sphincter and the degree of emptiness of pot-bellied abdomen. X-ray examination is also an important imaging tool for the diagnosis of megacolon. Through the child’s symptoms combined with physical examination and X-ray examination can basically clarify the diagnosis. Children with megacolon can have their bowel function reconstructed through surgery, and most of them can regain normal bowel capacity after active treatment. It is recommended that children with megacolon are actively seeking medical attention.