Azithromycin has a certain effect on the liver, especially for some patients, if there is a combination of viral hepatitis or other reasons resulting in poor liver function, in this case, the use of azithromycin may cause azithromycin, azithromycin may cause the rise of glutamic oxaloacetic transaminase, azithromycin. So for patients with underlying liver disease, the drug should be avoided as much as possible. Some patients need to consider moderate use of some liver-protecting drugs for active treatment while using antibiotics. For some patients, blood should be drawn in time to do liver function test, if it suggests that there is an elevation of alanine aminotransferase and glutamic oxalate aminotransferase, intravenous hepatoprotective therapy is needed. In addition, for the use of antibiotics patients, but also to observe whether the renal function of the damage, if necessary, to be renal function, urine routine testing.