LDL cholesterol of 4.3 mmo/L is among the higher levels. The appropriate level of LDL cholesterol needs to be ≤3.4mmol/L, while the borderline level is between 3.4 and 4.1mmo/L. Generally, LDL cholesterol is considered to be elevated when it exceeds 4.1mmo/L. Therefore, at the diagnostic level, LDL cholesterol of 4.3 mmo/L is considered to be on the high side. Elevated LDL cholesterol is mostly due to genetic factors, and is also associated with overeating, insufficient exercise, and overweight. In addition, diseases such as hypothyroidism, nephrotic syndrome, cholestatic jaundice, and the use of drugs such as androgens, B-blockers, and glucocorticoids can also induce an increase in LDL cholesterol. Elevated LDL cholesterol can increase the risk of coronary heart disease because LDL cholesterol is a risk factor for atherosclerosis, and its increased level is positively correlated with the development of coronary heart disease. Therefore, when LDL cholesterol is elevated, it is important to identify the cause of the disease and target relief to avoid the adverse cardiovascular effects of elevated LDL cholesterol. If LDL cholesterol is found to be elevated, it is necessary to consult a doctor in time and follow the doctor’s instructions for examination and treatment, so as to avoid delaying the condition.