Colic, also generally called intestinal spasm, is a symptom in itself. The cause is not clear and may be related to diet, gastrointestinal hormones, gas accumulation in the gastrointestinal tract and other environmental factors and vascular lesions or tumors. It mostly occurs in the small intestine, with abdominal pain mostly around the umbilicus, often accompanied by vomiting, and in severe cases, there may be cold sweats, pallor, chills in the hands and feet, and unbearable pain. Colic is mostly sudden abdominal pain of paroxysmal onset, usually each attack lasts mostly 3-5 minutes, and each attack may be separated by minutes to hours, usually relieved after 10 minutes to hours, and individual attacks may recur for several days. In infants under 3 months of age, colic attacks are characterized by paroxysmal crying that is difficult to soothe, sometimes with flushing of the face, bending of the legs, tension in the abdominal wall, and distension of the abdomen. It usually occurs at night and can last for several hours, and can be terminated by the infant’s exhaustion of gas, bowel movements or force. Intestinal cramps may begin in the first week of life, resolve by the eighth week, and gradually disappear by 3-4 months of age. When the patient has paroxysmal abdominal pain with significant abdominal distension and vomiting, hot compresses and massage are ineffective, he or she should seek prompt medical attention. When infants with colic do not heal themselves under warm conditions and cry more than once and cannot be soothed, they should promptly go to the hospital for treatment.