Masturbation once every two days is not harmful to the kidneys, but it is not advocated. The main function of the kidneys is excretion, filtering water and metabolic wastes in the blood, maintaining the stability of the internal environment of the body; masturbation refers to their own reproductive organs, sexual stimulation, to solve the sexual distension, in order to obtain sexual pleasure and solace. Therefore, generally speaking, masturbation is not very much related to the kidneys. However, it does not mean that excessive masturbation is harmless. Frequent masturbation may cause lack of energy, indulgence in sexual pleasure or sexual fantasies, affecting normal work and study, and may also lead to prostatitis and urinary tract infections. Patients with abnormal renal function are advised to consult regular hospitals, improve relevant examinations and carry out targeted treatment under the guidance of physicians.