Many diseases (such as nephrotic syndrome, lupus, etc.) require long-term hormone therapy, blisters in the mouth after taking hormones may be a viral infection caused by low immunity (requiring antiviral therapy), or pemphigus (requiring hormone, immunosuppressant and other treatments), which need to be analyzed specifically. 1. viral infection: viral infection (such as herpes virus, etc.) can lead to blisters in the mouth, may also be accompanied by fever, headache, fatigue and other symptoms, blister fluid smear to find inclusion bodies and other tests can assist in the clear diagnosis, the need for rest, antiviral and nutritional therapy, etc., it is recommended that timely dermatology, under the guidance of the doctor to the correct treatment. 2. pemphigus: is an autoimmune disease, oral mucosa can appear blisters, blisters can also occur in other parts of the body, can be accompanied by malnutrition and other symptoms, blister fluid smear pathology examination can assist in the clear diagnosis of the need for timely dermatology, under the guidance of the doctor to correctly carry out the hormone, immunosuppressive drugs and other medications, to avoid delays in the condition. The first thing you need to do is to take the hormones and get the blisters in your mouth, so you can get a clear diagnosis and the right treatment to avoid delays, and don’t take any medication.