The appearance of jelly-like particles after the semen is discharged from the body requires consideration of two reasons: physiological on the one hand and pathological on the other. The physiological reason is that when semen is first discharged from the body, it looks jelly-like in order to protect the sperm, and the jelly-like particles will gradually disappear in about 30 minutes, which is the process of semen liquefaction. If it is still jelly-like for more than 30 minutes, it is considered that the semen is not liquefied and is caused by inflammation of the genitourinary system such as orchitis, prostatitis and epididymitis. Semen non-liquefaction has a great impact on male fertility. Sperm do not get a swimming environment and cannot reach important parts of the tube such as the cervix, uterus and fallopian tubes, and difficulties in conception occur. It is recommended to have timely examination and treatment.