Whether or not urinary protein 2+ will continue to progress is related to the cause of urinary protein. The causes of urinary protein include physiological factors and pathological factors. Physiological factors such as overwork, strenuous exercise can appear after the urine protein, usually remove the trigger, can return to normal, will not continue to progress on the body. Pathological factors such as acute and chronic glomerulonephritis, urinary tract infections, tumors can cause urinary protein 2 +, usually indicates that the kidney function is damaged, if not actively treated, the kidney function continues to decline, will lead to serious consequences, such as renal failure, and continue to develop the uremia stage. Urinary protein is an independent risk factor for kidney injury, can cause kidney fibrosis, long-term urine protein will cause kidney function will gradually decline, the more urine protein the greater the damage. Therefore, if the examination found that the urine protein 2 +, should be timely consultation, improve the relevant examination, clear cause, for the cause to do standardized treatment, to avoid self-medication, bring adverse consequences.