Small blisters on the soles of the feet, accompanied by itching and peeling symptoms, the treatment should be the cause of treatment, this situation is likely to be caused by fungal infections, allergies caused by eczema and sweat herpes, etc., a clear diagnosis can be given to the drug treatment. 1. Fungal infections: that is, usually called foot fungus, there will be such a symptom, after a clear diagnosis, can be under the guidance of the doctor, the application of drugs to give treatment, such as topical application of miconazole ointment, naftifine ketoconazole cream and other treatments. 2. Eczema caused by allergy: often occurring on the soles of the feet, can be determined, take anti-allergy drugs, such as levocetirizine hydrochloride capsules, and with the topical ointment, such as fluticasone propionate ointment, halometasone ointment and so on to give treatment. 3. Sweat herpes: patients will have blisters on the soles of the feet, and the range will be more extensive, there is no fungal infection, you can follow the doctor’s advice to give treatment with topical glycerine lotion, in the treatment at the same time, pay attention to the foot ventilation, dry, so as to avoid further aggravation of sweat herpes. It is recommended to go to a nearby regular hospital, with the help of a professional doctor, to determine the specific cause of the disease through the examination, and then give treatment, so as to avoid misdiagnosis and delay the condition.