Small focal adenoepithelial low-grade intraepithelial neoplasia of the intestine belongs to the results of pathologic examination, a diagnosis of lesions in the intestine, which require further treatment. Small localized lesions in the intestinal tract detected by colonoscopy and the final pathological findings show cellular anomalies, but the degree of malignancy is relatively low, belonging to the earliest stage of atypical hyperplasia, and are diagnosed as small foci of adenoepithelial low-grade intraepithelial neoplasia. The corresponding lesion is a precancerous lesion, which may progress if not controlled in time and requires further treatment. Most of the endoscopic radical resections for the corresponding lesions can be performed, and most of them can reach a complete state after the operation with further judgment of gross pathology. Small intestinal foci of adenoepithelial low-grade intraepithelial neoplasia, the emergence of enlargement or obvious abdominal pain, bleeding and other symptoms, we should consult a doctor in a timely manner for examination, after a clear diagnosis, standardized treatment under the guidance of clinicians.