Pimples are generally referred to as acne. Acne on both sides of the cheeks may be caused by androgen abnormalities, use of harsh cosmetics, and bad lifestyle habits. 1. Androgen abnormality: If women or men are in the developmental period, this will lead to excessive secretion of androgen, which will make the sebaceous glands secrete a lot of oil, which may lead to clogging of hair follicles, causing acne on both sides of the cheeks. 2. The use of bad cosmetics: If patients use poor-quality cleansers in their daily life and do not do a good job of skin cleansing, the chemical ingredients in the poor-quality cleansers may block the follicle openings, which may cause inflammation and lead to acne on both sides of the cheeks. 3. Bad life habits: If the patient in daily life, mental stress or long-term late night, may make the body in the state of endocrine imbalance, coupled with the body’s low immunity, may be in the Propionibacterium acnes stimulation, triggering local inflammatory reaction, the symptoms of cheeks on both sides of the long acne. When patients with acne on both sides of the cheeks, they need to go to the hospital in time for a comprehensive examination, to clarify the cause of the disease, and then choose the appropriate method of symptomatic treatment under the guidance of the doctor.