What is affluenza? “Affluenza” is not a “disease” In today’s society, affluenza has become a major health hazard to humans. Affluenza, also known as “modern civilization disease”, is a non-contagious epidemic disease caused by people entering modern civilization, living in better and better conditions, eating well, eating well, over-nutrition, and reducing activity, such as constipation, obesity, intestinal cancer, hyperlipidemia, atherosclerosis, coronary heart disease, diabetes, stroke, etc. The occurrence and development of “affluenza” is very closely related to the bad habits of urban people, such as smoking, alcoholism, unreasonable dietary structure, lack of necessary fitness exercise. Bad environment such as environmental pollution, food pollution, air pollution, water pollution can also cause people to suffer from affluenza. In addition, diseases such as obesity, intestinal cancer, hyperlipidemia, coronary heart disease and diabetes itself have a large genetic factor in their development. Common rich disease “rich” shall not “disease” 1, obesity is obesity is the body fat, especially triglycerides (triacylglycerols) accumulation of excessive and lead to a state. Usually due to excessive food intake or body metabolism changes and lead to excessive accumulation of body fat, resulting in excessive weight growth, and cause human pathophysiological changes. According to the different causes of obesity, obesity can be divided into simple obesity and secondary obesity two categories. Simple obesity has no clear cause, may be related to genetics, diet and exercise habits and other factors. Secondary obesity refers to the obesity caused by other diseases. Obesity is an important factor affecting human health, and obesity can cause a variety of chronic diseases, such as hypertension, cardiovascular disease, diabetes, etc. In recent years, the size of the obese population in China has grown rapidly. According to the World Health Organization, in 1982, 7% of China’s population was considered overweight; by 2006, that percentage had risen to 15%; today, one out of every four adults is overweight. As of 2010 data, China’s current obese population of 325 million people, and this number may also double in the next 20 years. Diabetes is a group of metabolic diseases characterized by hyperglycemia due to defective insulin secretion and/or insulin action disorder. Continuous hyperglycemia and long-term metabolic disorders can lead to damage to tissues and organs throughout the body, especially the eye, kidney, cardiovascular and nervous system, as well as its dysfunction and failure. Severe cases can cause acute complications such as ketoacidosis and hypertonic coma, including water loss, electrolyte disorder and acid-base balance disorder. The clinical manifestations are three more and one less, i.e. polyuria, polydipsia, polyphagia and wasting, while some‖ diabetic patients have atypical symptoms, only dizziness, weakness, etc., or even no symptoms. Acute complications of diabetes may include loss of appetite, nausea, vomiting, abdominal pain, increased polyuria, dizziness, drowsiness, blurred vision, dyspnea, coma, etc. In early 2010, The New England Journal of Medicine published a study by the Chinese Medical Association’s Diabetes Research Group on Diabetes and Metabolic Syndrome. “This survey showed that in 2010, compared to 1994, the risk of diabetes was significantly higher among people with low income in China, and that household income was no longer a risk factor for the development of diabetes. Hypertension Hypertension is the most common chronic disease and the most important risk factor for cardiovascular disease, with stroke, myocardial infarction, heart failure and chronic kidney disease as its major complications. The definition and classification of hypertension sets the diagnostic criteria for hypertension at a systolic blood pressure ≥ 140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg. The prevalence of hypertension increases with age; the prevalence is slightly lower in women than in men before menopause, but rises rapidly after menopause, even higher than in men; the prevalence is higher in colder regions at high latitudes than in warmer regions at low latitudes, and higher at high altitudes than at low altitudes. Related to dietary habits, the higher the salt and saturated fat intake, the higher the average blood pressure level and prevalence. The prevalence of hypertension in our population has two relatively significant features: the prevalence of hypertension tends to increase from the south to the north; there are also some differences in the prevalence of hypertension among different ethnic groups, with higher prevalence among ethnic groups living in the north or highland areas and lower prevalence among ethnic groups living in the south or non-highland areas; such differences may be related to geographic environment and lifestyle, and no differences have been found among ethnic groups No significant genetic background differences have been found among ethnic groups. 3, coronary heart disease Coronary heart disease is referred to as coronary heart disease. Due to abnormal lipid metabolism, lipids in the blood are deposited on the originally smooth arterial intima, and some atherose-like lipids accumulate in the arterial intima to form white plaques, which gradually increase and cause narrowing of the arterial lumen and obstruction of blood flow, leading to heart ischemia and angina pectoris. If the plaque on the arterial wall forms an ulcer or ruptures, a thrombus will form, completely interrupting the blood flow of the entire blood vessel and causing acute myocardial infarction or even sudden death. A rare pathogenesis of coronary artery disease is spasm of the coronary arteries (the vessels can be without atherosclerosis), producing variant angina, which can also lead to acute myocardial infarction (or even sudden death) if the spasm lasts more than 30 minutes. The causes of atherosclerosis are not fully understood and may be the result of a combination of factors. Risk factors for the development of this disease are considered to be age and gender (men over 45 years old, women over 55 years old or postmenopausal), family history, dyslipidemia, hypertension, urinary glucose disease, smoking, overweight, obesity, gout, and inactivity. Gout Gout is a metabolic disease that is closely related to life. Modern people’s standard of living has improved, eating and drinking is a common thing, and it is not known how much diet related to the onset of gout is consumed, which makes the cases of gout attack increasing day by day. Therefore, it is also considered a disease of affluence. Gout develops when the concentration of uric acid in the blood is too high, forming uric acid crystals that are deposited in the tissues. If deposited in the joints, it causes arthritis, and in the kidneys, it leads to kidney stones. Gout occurs most often in middle-aged and elderly people, obese people and people with intellectual disabilities. Acute gouty arthritis mostly occurs in the small joints of the lower extremities, especially the first toe-metatarsal joint. Moreover, it often develops suddenly at night with localized redness, swelling and severe pain in the affected joints, and is extremely sensitive to temperature, touch and vibration. Gout is prone to recurrence, and after repeated attacks, it can involve several joints and lead to joint deformities, and can also cause serious kidney function damage. A small number of patients start with kidney stones and may have symptoms such as back pain and hematuria.