Peeling at the corners of the mouth is generally related to many aspects of the factors, such as dry weather, dehydration of the organism, bad habits, physical and chemical stimuli, lack of vitamins and so on. 1. Dry weather: such as the fall and winter seasons, the weather is cold and dry, which will cause a lack of moisture on the surface of the skin, if you do not replenish the water in time, you may have skinned corners of the mouth. 2. Lack of water in the body: including drinking too little water will lead to lack of water in the body, if you don’t pay attention to the moisturizing care of the skin in a timely manner will easily lead to lack of water on the surface of the skin, resulting in peeling at the corners of the mouth. 3. Bad habits: for example, patients often lick the corners of the mouth, smoking, drinking alcohol, etc., for a long time to repeatedly stimulate the corners of the mouth is easy to lead to the corners of the mouth peeling phenomenon. 4. Physical and chemical stimulation: excessive exposure to sunlight can cause solar lentigines, the corners of the mouth will appear dry skin phenomenon. In addition, irritating drugs, cosmetics and other local stimulation can also cause the corners of the mouth peeling. 5. Lack of vitamins: such as lack of vitamin B, vitamin C, etc., affecting the cellular oxidation process, thus causing keratitis, oral ulcers and other lesions, can also lead to the corners of the mouth peeling.