Varicose veins of the lower limbs can be divided into six stages, stage 1 to 3 belongs to the early stage of the disease with mild symptoms and stage 4 to 6 belongs to the late stage of the disease with more severe symptoms. Stage 1: There is no obvious manifestation, but you can see the blue color stripes distribution in the calf. Stage 2: the skin veins of the lower limbs can be found protruding when standing, and disappear when sitting down. Stage 3: Obvious skin varicose veins appear and are accompanied by edema, soreness and heaviness on the affected side of the calf. Stage 4: In addition to varicose veins, there may be obvious skin changes, such as hyperpigmentation of the skin surface, hardening of the skin, etc. There may also be a drop in the skin temperature of the calf, coldness at the end of the lower limbs, etc. Stage 5: It is manifested as the wound or breakage in the calf, and the wound is difficult to be healed. Stage 6: it is gangrene stage, which is characterized by recurrent leg ulcers, necrosis of part of the skin, and accompanied by severe pain. Currently the treatment of varicose veins of the lower limbs is more mature, once suffering from varicose veins of the lower limbs should immediately seek medical treatment under the guidance of doctors to prevent further deterioration of the disease.