Infertility has caused great trouble and even family disputes to many married and pregnant women. Long-term infertility of female friends most often do is to gynecology for systematic examination or treatment, many times after the examination or systematic treatment of the stomach still do not see movement of the case, disheartened and ultimately have no choice but to choose in vitro, which is the current major hospitals in the reproductive center of the reason for the overflow of patients, crowded with many times in the disappointment of the last hope of the people looking for hope. If you can’t find the cause of your long-term infertility, maybe it’s time to change your perspective, change your clinic, and check for high-risk HPV virus infection. I want to remind you that if you can’t find a reason for years of infertility, maybe it’s time to consider whether the HPV virus is to blame. HPV, or human papillomavirus, has more than 200 subtypes identified. Low-risk types can cause flat warts, condyloma acuminatum, etc., and high-risk types are associated with cervical cancer, rectal cancer, oral cancer, etc. It has been confirmed that persistent infection with high-risk HPV viruses is a necessary factor for cervical cancer, and more than 90% of cervical cancers are accompanied by high-risk HPV infection. For infertile female friends may say, I am most concerned about infertility, is the HPV virus and infertility have anything to do with it? The more common causes of female infertility are: ovulation disorders, fallopian tube factors, endometrial tolerance abnormalities mainly, if the gynecological examination and treatment for a long time, still not solve the problem, you need to consider whether the “door” is broken, and here refers to the door that is the female cervix. HPV virus has no precise and direct relationship with infertility, but cervical inflammation and infertility have a certain relationship. Inflammation of the cervical canal and infertility have a definite relationship. The cervical canal is the passageway for sperm to travel up to the uterine cavity, and the mucus secreted by the glands of the cervical canal provides a favorable environment for sperm activity, as well as a screening function. If you suffer from cervical inflammation, the composition and character of the cervical mucus will change, the mucus in the bacterial increase, become purulent turbid. A study showed that 85% of infertile women have staphylococcus, streptococcus, trichomonas, and gonorrhea infections in their cervical mucus, and a higher detection rate of mycoplasma. Inflammation of the cervix interferes with the movement and transportation of sperm through the female reproductive tract, leading to infertility, which can be referred to as the “cervical barrier” or the “cervical canal cause”. This is called “cervical barrier” or “cervical canal cause”. It accounts for about 10-20% of all causes of infertility. The HPV virus itself does not cause inflammatory reactions such as visible redness and swelling of the cervix, which means that the HPV virus does not cause inflammatory reactions. However, it can cause symptoms of increased, sticky leukorrhea. If cervicitis is combined with HPV infection, the HPV-induced increased leukorrhea, sticky and snotty discharge on top of the inflammation of the cervical canal can worsen thereby leading to blockage of the cervical canal and infertility problems. High-risk HPV viruses are first addressed along with lesions and inflammation using a comprehensive approach, followed by virus clearance. Clinical practice also shows that as the HPV virus is removed, the abnormal vaginal discharge disappears, and the inflammation of the cervical canal is also resolved, so that patients with cervical canal inflammation combined with HPV virus infection are more likely to conceive after the factors causing infertility have disappeared.